BioSNTR research objectives

The research program is organized around two Driving Biological Projects

  1. Understanding how cell surface receptors control the function of macrophages, which allows researchers to gain fundamental knowledge about the membrane environment and protein networks work together to integrate receptor inputs to shape both acute responses such as phagocytosis as well as the transcriptional program governing macrophage function (animal frontier)
  2. Gaining the ability to manipulate symbiotic nodule development in soybeans and other crops to enhance fixation and reduce the use of chemical fertilizers.  The objectives are to (1) elucidate the spatio-temporal relationship between mrR160, auxin, and cytokinin during nodule development, and (2) to determine how spatio-temporal signaling and hormone action dictate the development of specific nodule zones (plant frontier)
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Driving Biological Project 1 (DBP 1)

Receptor Control of Immune Cell (Macrophage) Function
Understanding how immune cells (macrophages) respond to infections at a molecular & cellular level allows us to develop therapeutics and implantable materials that can assist and accelerate the healing process.

DBP1 Chart

 

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Driving Biological Project 2 (DBP 2)

Nodule Development in Soybeans
Understanding what occurs at the
molecular & cellular level of the soybean root allows us to make modifications to create better performing soybean plants.

DBP2 Chart