Dr. Hoppe is collaborating with the Drubin Lab at UC Berkeley to use genome-editing to insert genes coding fluorescent proteins (FP) in-frame with the coding regions for proteins of interest. They have recently launched a new project that will use genome-editing to study the interplay between membrane curvature and the assembly of molecular signaling complexes on the plasma membranes of living cells. Here this technology will be used to make precise genetic manipulations in short periods of time for modulating signaling pathways for testing tissue engineering approaches. The infrastructure for application of genome-editing to tissue engineering will be disseminated to BioSNTR by technician Jason Kerkvliet, who is currently working with the technology in the Hoppe Lab. He will provide the expertise and training needed for genomic editing in plant and animal cells.