Darci Fink

Darci Fink, PhD

Assistant Professor
South Dakota State University
Chemistry & Biochemistry
(605) 688-5873

Dr. Fink’s research team uses live imaging, including intravital two-photon microscopy, in mouse models of inflammation and malignancy to study lymphatic vessel remodeling.  Their work focuses on the contributions of macrophages to vessel assembly and regression and the role of altered lymphatic endothelial cell biology in tumor cell entry into and metastasis through lymphatic vessels.  She has established exciting collaborations to develop a new class of bio-imaging tool – fluorescent organic nanoparticles – and to study primary cilia in development and disease.  Dr. Fink received her PhD in Cancer Research from the University of Nebraska Medical Center and was trained in the laboratories of Dr. Michael A. Hollingsworth and Dr. Richard M. Tempero (Boys Town National Research Hospital, Omaha, NE).

Areas of expertise:
Lymphatic vascular remodeling, rumor microenvironment, intravital imaging, two-photon microscopy, mouse models, mouse surgery

Selected publications:
The lymphatic system and pancreatic cancer
Darci M. Fink, Maria M. Steele, and Michael A. Hollingsworth.  Cancer Lett. 2015 Dec 29. pii: S0304-3835(15)00745-4. doi: 10.1016/j.canlet.2015.11.048. [Epub ahead of print].

NGF regulates neurolymphatic remodeling during corneal inflammation and resolution
Darci M. Fink, Alicia L. Connor, Philip M. Kelley, Maria M. Steele, Michael A. Hollingsworth, and Richard M. Tempero.    PLoS One. 2014 Nov 10;9(11):e112737. doi: 10.1371/journal.pone.0112737. eCollection 2014.

Soil microbial community response to corn stover harvesting under rain-fed, no-till conditions at multiple US locations
R. Michael Lehman, Thomas F. Ducey, Virginia L. Jin, Veronica Acosta-Martinez, Carla M. Ahlschwede, Elizabeth S. Jeske, Rhae A. Drijber, Keri B. Cantrell, James R. Frederick, Darci M. Fink, Shannon L. Osborne, Jeff M. Novak, Jane M. F. Johnson, and Gary E. Varvel.  Bioenergy Research (2014) 7:540-550.


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